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agner-PaleoMama-guest-blogger-@-AChildAfter40.com_.jpg">PaleoMama-guest-blogger-@-AChildAfter40.com_-250x165.jpg" alt="" width="409" height="269" />By Darja Wagner, Ph.D., Molecular Biology, paleo-mama.com.
For women over 40 who don’t have much time to waste, scientists are making groundbreaking advances in IVF technology.
Innovative research performed at TCART (Toronto Center for Advanced Reproductive Technology) and its subsequent results were reported at the Society for Reproductive Investigation (SRI) 62nd Annual Scientific Meeting, in March 2015.
In brief, a multi-center clinical trial (http://www NULL.ovascience NULL.com/files/SRI_Poster_Casper_March_2015_FINAL NULL.pdf) that brought together stem cell biologists from the USA, patients from Turkey, and teams of Canadian reproductive specialists led by Drs. Robert F.Casper and Yaakov Bentov, demonstrated for the first time that the injection of a patient’s own mitochondria (these are energy producers present in dozens or even hundreds in every cell) into the egg would improve embryonic development in fertility treatments and result in better pregnancy rates.
The important thing here is that the energy levels of eggs change as a woman ages, leading to lower CoQ10 (http://www NULL.ctvnews NULL.ca/supplement-touted-as-way-to-extend-fertility-1 NULL.744549) and ATP levels and reduces the likelihood of conception and correct embryonic development.
To counteract this, scientists transferred young fresh mitochondria from the egg-precursors (which are normally present in the ovarial lining) into the maturing egg itself, energizing the egg and making it more likely to produce healthy embryos and babies. It worked!
Several women with histories of failed IVF and poor egg quality got pregnant. Pregnancy rates of close to 50% were achieved in preliminary attempts, which is very impressive given the typical 30% IVF success rate and the fact that these patients had challenging infertility histories.
The process of egg rejuvenation (egg-Botox, so to speak!) is a new procedure and certainly warrants further research. The preliminary data are very hopeful and the method could easily become a real breakthrough in fertility treatments for women over 40 and women with compromised egg quality.
ABOUT THE AUTHOR: Darja Wagner, Ph.D. is a scientist specializing in vitamins and hormones. She is the author of the blogs Get Pregnant After 35 (http://www NULL.paleo-mama NULL.com) and Improve Egg Quality (http://www NULL.eggqualityimprove NULL.com), where she addresses fertility and getting pregnant for women of advanced reproductive age. She lives in Berlin with her husband and two sons, both of whom were born after the age of 35.
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